This will manifest as a vertical or horizontal bands that the pen seems to ignore. These bands will extend across the full active area of the tablet.
If normal strokes look like this:
Then missing horizontal bands will look like this:
And missing vertical bands will look like this:
Usually it seems to be a hardware issue. Something is wrong with the tablet itself.
It might also be cause be electromagnetic interference
Restart computer
Reinstall driver
Test tablet with another computer
Check if it happens with multiple applications
Check if it happens in the pressure test region of the tablet driver
If the problem persists, contact support.