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First try the Common drawing troubleshooting steps.
(https://www.reddit.com/r/wacom/comments/s6wdud/dots_appear_when_i_dont_put_one_why_does_this/)
(https://www.reddit.com/r/ClipStudio/comments/1011a69/big_dots_at_start_of_strokes_need_help/) - This was solved by reinstalling Clip Studio Paint